Potential SARS-CoV-2 Reinfection among COVID-19 Cases in the U.S.

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UPDATE: This data collection form is closed.

Dear colleagues,

Thank you for your interest in our investigation, “Potential SARS-CoV-2 Reinfection among COVID-19 Cases in the U.S.”. At this time, we are suspending case intake via the IDSA Emerging Infections Network. CDC is continuing with investigations of potential cases of re-infections.

If your institution:
1. Has stored respiratory specimens of SARS-CoV-2 since Feb, 2020
2. Has corresponding clinical records
3. Can identify repeat positive samples >90 days apart,
We would be interested in discussing partnered projects with you. Please reach out to us at eocevent461@cdc.gov.

Thank you again for all of you work for the care or our patients and our communities. We look forward to being in touch soon!

Sincerely,
Re-infections Team
CDC COVID-19 Response
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The purpose of this query is to facilitate case description. Please complete as much as feasible. If preferable, you may describe the case in its entirety using the final text box at the end of this query.


          Clinician's Information:
    Your name:
    Your email address:
    Your state of practice:   
    Patient's Demographic Information :
  1. Age group in years:   18-44    45-54    55-64    >=65
  2. Sex:   Male      Female

  3. COVID-19 Initial Presentation:
  4. Date of illness onset (approximate):   [MM/DD/YY]

  5. Symptoms (please separate each symptom by a comma):  

  6. Lab-confirmed SARS-CoV-2 infection?   Yes      No

  7. Illness severity:
    Mild to moderate (mild symptoms up to mild pneumonia)
    Severe (dyspnea, hypoxia, or >50% lung involvement on imaging)
    Critical (respiratory failure, shock, or multiorgan system dysfunction)

  8. Evidence of recovery:   [Select all that apply]
    Two consecutive negative RT-PCR results
    Resolution of symptoms, describe: 
    Radiographic evidence of recovery, describe: 

  9. Date of recovery:   [MM/DD/YY]
    (Note: where recovery is defined as at least 3 days have passed with no fever (without antipyretics) and improvement in symptoms and at least 10 days have passed since symptom onset or diagnosis (if asymptomatic).

  10. Comments about 1st course of illness:

  11. COVID-19 Recurrence:
  12. Date of illness onset (approximate):   [MM/DD/YY]

  13. Symptoms (please separate each symptom by a comma):  

  14. Lab-confirmed SARS-CoV-2 infection?   Yes      No

  15. Illness severity:
    Mild to moderate (mild symptoms up to mild pneumonia)
    Severe (dyspnea, hypoxia, or >50% lung involvement on imaging)
    Critical (respiratory failure, shock, or multiorgan system dysfunction)

  16. Evidence of recovery:   [Select all that apply]
    Two consecutive negative RT-PCR results
    Resolution of symptoms, describe: 
    Radiographic evidence of recovery, describe: 

  17. Date of recovery:   [MM/DD/YY]
    (Note: where recovery is defined as at least 3 days have passed with no fever (without antipyretics) and improvement in symptoms and at least 10 days have passed since symptom onset or diagnosis (if asymptomatic).

  18. a. Comments about 2nd course of illness:
    b. Did the patient remain asymptomatic between the initial and recurrent episodes?
        Describe:

  19. SARS-CoV-2 Testing History:
    Date
    MM/DD/YY
    Specimen
    Type
    Test
    Type
    Result PCR CT
    value
    Copy of Report
    Available?
    1.                  
    2.                  
    3.                  
    4.                  
    5.                  
    6.                  
    7.                  
    8.                  
    9.                  
    10.                  
    11.                  
    12.                  
    If any stored samples are available, please indicate the dates for which tests listed above:

    We would ideally like to receive paired respiratory samples for molecular testing (e.g., PCR, culture, sequence) and paired plasma OR serum for serological testing; paired means samples obtained from first clinical episode and the recurrent episode. We can provide additional details, if requested.

    Please provide additional comments about this suspected case:


    May we contact you if more information is necessary to understand your case and if additional steps are needed?   Yes      No
    Telephone number for contact:  

    Both the CDC IRB and the University of Iowa IRB have determined that this project meets the requirements of public health surveillance (not research) as defined in 45 CFR 46.102(l)(2). No further review is required.